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Connect PolyAI to telephony, CRM, hospitality, healthcare, and knowledge platforms. Integrations let your agent access external systems during calls — hand off to live agents, look up reservations, create support tickets, or pull knowledge base articles. All integrations listed here are available from Configure > Integrations in Agent Studio.

Telephony

Connect PolyAI to your contact center platform for call routing, transfers, and live agent handoffs.

Five9

Multi-tenant SIP trunk for call routing and management

NICE CXone

Integrate using the Signal API

Twilio

Flex contact center integration with handoffs

Amazon Connect

Voice agent integration with Amazon Connect

Genesys

Connect via Genesys Cloud BYOC

Zendesk Talk

Route calls and hand off to agents via SIP

Dialpad

Voice automation with Dialpad

Chat

Connect PolyAI to messaging channels for text-based conversations.

SMS

Send and receive text messages
WhatsApp and Salesforce Chat integrations are available in the Studio UI. Documentation for these is coming soon.

CRM

Connect to your CRM platform for caller context, ticket management, and customer data lookup.

Salesforce CRM

Access customer records and manage cases
Zendesk CRM, HubSpot, and Microsoft Dynamics 365 integrations are also available in the Studio UI. Documentation for these is coming soon.

Hospitality

Booking management for restaurants and hotels — look up, create, and modify reservations in real time.

OpenTable

Restaurant reservation management

HotSOS

Automate room service and maintenance requests
Cendyn is also available in the Studio UI. Documentation is coming soon.

Healthcare

Integrate with electronic health record (EHR) systems for scheduling, patient data, and clinical workflows.

Epic

Connect to Epic EHR for patient data access
ModMed, athenaOne, Cerner (Oracle Health), and Raintree integrations are available in the Studio UI. Documentation for these is coming soon.

Knowledge base

Connect external knowledge sources so your agent can retrieve articles and answers during calls.

Gladly

Pull articles from your Gladly knowledge base
Zendesk Knowledge Management, Salesforce Knowledge Management, and Azure AI Search integrations are available in the Studio UI. Documentation for these is coming soon.

Don’t see your platform?

If your system isn’t listed above, you can build a custom integration using the APIs tab. Define HTTP endpoints, configure per-environment base URLs and authentication, and call them from Python functions using conv.api — no pre-built connector needed.For integrations not available in the Studio UI (Custom SIP, PCI Pal, Stripe, and others), see the Managed services section.
Last modified on March 30, 2026